Syringe dead space: difference between revisions
Diff·revision 14 → 15·20:52, 22 Dec 2025
Difference between revision 14 and revision 15 of Syringe dead space. 4 lines changed; the page grew by 198 bytes.
| Revision 14 — 22:45, 14 Dec 2025 SubQ_Solveig (talk) expand §Measured and computed magnitudes 15,689 bytes +261 | Revision 15 — 20:52, 22 Dec 2025 LyophilLena (talk) state that swirling rather than shaking is the handling convention, sourced 15,887 bytes +198 | ||
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| 101 | | 0.100 mL | 0.300 mL | 6 | 40% | | 101 | | 0.100 mL | 0.300 mL | 6 | 40% | |
| 102 | 102 | ||
| + | 103 | Figures assume that the entire nominal fill is accessible, which overstates yield: liquid trapped by vial geometry is additional and is not counted here. | |
| + | 104 | ||
| 103 | === Priming and air management === | 105 | === Priming and air management === |
| 104 | The mechanism by which the dose error arises is the presence of gas where liquid is assumed. Descriptions of injection technique in manufacturers' [[Prescribing information|prescribing information]] and in nursing references accordingly treat expulsion of air before the dose is measured as a defined step, and treat the graduation as valid only for a gas-free barrel and hub.{{r|who2015}} | 106 | The mechanism by which the dose error arises is the presence of gas where liquid is assumed. Descriptions of injection technique in manufacturers' [[Prescribing information|prescribing information]] and in nursing references accordingly treat expulsion of air before the dose is measured as a defined step, and treat the graduation as valid only for a gas-free barrel and hub.{{r|who2015}} |
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| 117 | 119 | ||
| 118 | In vaccination and pandemic preparedness, dead space determines how many doses can be drawn from a fixed vial, and therefore how far a constrained supply extends. Analyses during influenza-preparedness planning noted that substituting devices of a few microlitres of dead space for devices of 70–80 µL could increase the number of doses obtainable from a multi-dose presentation by a substantial fraction, and that the effect is proportionally larger the smaller the dose.{{r|strauss2006,who2015}} | 120 | In vaccination and pandemic preparedness, dead space determines how many doses can be drawn from a fixed vial, and therefore how far a constrained supply extends. Analyses during influenza-preparedness planning noted that substituting devices of a few microlitres of dead space for devices of 70–80 µL could increase the number of doses obtainable from a multi-dose presentation by a substantial fraction, and that the effect is proportionally larger the smaller the dose.{{r|strauss2006,who2015}} |
| + | 121 | ||
| + | 122 | Design approaches fall into three groups: | |
| 119 | 123 | ||
| 120 | == References == | 124 | == References == |