Karl Fischer titration: difference between revisions
Diff·revision 22 → 23·21:59, 4 Jul 2025
Difference between revision 22 and revision 23 of Karl Fischer titration. 8 lines changed; the page grew by 357 bytes.
| Revision 22 — 18:09, 15 Jun 2025 SecondarySrc_Seb (talk) give the injection volume, without which the loading cannot be judged 7,949 bytes ±0 | Revision 23 — 21:59, 4 Jul 2025 Retention_Time_Rae (talk) add the reference standard and its traceability 8,306 bytes +357 | ||
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| 81 | — roughly 13% below the label figure. Whether that constitutes [[Underfilling|underfilling]] depends entirely on whether the label claim is a gross fill weight or a net peptide claim, a distinction certificates frequently leave implicit and which [[Project:Sourcing_guidelines|this wiki treats as unresolved]] unless the supplier states it.{{r|usp1503}} | 81 | — roughly 13% below the label figure. Whether that constitutes [[Underfilling|underfilling]] depends entirely on whether the label claim is a gross fill weight or a net peptide claim, a distinction certificates frequently leave implicit and which [[Project:Sourcing_guidelines|this wiki treats as unresolved]] unless the supplier states it.{{r|usp1503}} |
| 82 | 82 | ||
| + | 83 | {{figure|vial|Cross-section of a lyophilised vial. The cake is hygroscopic and its water content is part of the labelled mass.}} | |
| + | 84 | ||
| + | 85 | == Relationship to other methods == | |
| + | 86 | {{seealso|Loss on drying|Analytical method validation}} | |
| + | 87 | ||
| 83 | == References == | 88 | == References == |
| 84 | {{reflist}} | 89 | {{reflist}} |
| ⋮ | ⋮ | ||
| 90 | * International Council for Harmonisation, ''Q6A: Specifications'' — the framework within which a moisture specification is set and justified. | 95 | * International Council for Harmonisation, ''Q6A: Specifications'' — the framework within which a moisture specification is set and justified. |
| 91 | * Isengard H-D. "Water determination — scientific and economic dimensions." ''Food Chemistry'' 106(4):1393–1398 (2008). | 96 | * Isengard H-D. "Water determination — scientific and economic dimensions." ''Food Chemistry'' 106(4):1393–1398 (2008). |
| + | 97 | ||
| + | 98 | == External links == | |
| + | 99 | * [https://www.usp.org/ USP General Chapters index] — Compendial chapters are paywalled; the index is public. | |
| 92 | 100 | ||
| 93 | == See also == | 101 | == See also == |