Karl Fischer titration: difference between revisions
Diff·revision 11 → 12·17:40, 13 Nov 2024
Difference between revision 11 and revision 12 of Karl Fischer titration. 5 lines changed; the page grew by 184 bytes.
| Revision 11 — 15:40, 28 Oct 2024 IncretinIvo (talk) convert a hard-coded date to the house format 4,966 bytes +155 | Revision 12 — 17:40, 13 Nov 2024 ChromCleanupCass (talk) expand §Volumetric and coulometric variants 5,150 bytes +184 | ||
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| 1 | {{Infobox method | 1 | {{Infobox method |
| 2 | | name = Karl Fischer titration | 2 | | name = Karl Fischer titration |
| + | 3 | | subtitle = Water determination | |
| 3 | | image = coa-sheet.svg | 4 | | image = coa-sheet.svg |
| 4 | | caption = Water content appears on a certificate of analysis alongside purity and peptide content. | 5 | | caption = Water content appears on a certificate of analysis alongside purity and peptide content. |
| ⋮ | ⋮ | ||
| 11 | | Reported precision = ≈1–3% relative at 1–10% w/w | 12 | | Reported precision = ≈1–3% relative at 1–10% w/w |
| 12 | | Sample size = 10–100 mg lyophilised solid | 13 | | Sample size = 10–100 mg lyophilised solid |
| + | 14 | <!-- Compendial references --> | |
| + | 15 | | USP = General Chapter <921>, Method Ia/Ic | |
| + | 16 | | Ph. Eur. = Method 2.5.12 | |
| + | 17 | | Sample destruction = Destructive | |
| 13 | }} | 18 | }} |
| 14 | {{hatnote|For the alternative gravimetric approach, see [[Loss on drying]]. For what water content implies about vial contents, see [[Peptide content]].}} | 19 | {{hatnote|For the alternative gravimetric approach, see [[Loss on drying]]. For what water content implies about vial contents, see [[Peptide content]].}} |