Reconstitution calculator: difference between revisions
Diff·revision 13 → 14·03:56, 27 Mar 2025
Difference between revision 13 and revision 14 of Reconstitution calculator. 7 lines changed; the page grew by 731 bytes.
| Revision 13 — 14:32, 11 Mar 2025 LurkerLevi (talk) add the medical-disclaimer cross-link to the tool pages 5,276 bytes ±0 | Revision 14 — 03:56, 27 Mar 2025 SchemaSorcha (talk) add the citation for the stability figures taken from the labelling 6,007 bytes +731 | ||
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| 52 | A vial labelled 10 mg with 5.2% water and 6.4% trifluoroacetate contains approximately | 52 | A vial labelled 10 mg with 5.2% water and 6.4% trifluoroacetate contains approximately |
| 53 | 53 | ||
| + | 54 | {{math|10 × (1 − 0.052 − 0.064) ≈ 8.7\,mg}} | |
| + | 55 | ||
| + | 56 | == Volume displacement and dead space == | |
| + | 57 | Two systematic effects are worth stating because the calculator does not model the first and only optionally models the second. | |
| + | 58 | ||
| + | 59 | '''Displacement.''' Adding 2 mL of diluent to a vial containing 5 mg of solid produces slightly more than 2 mL of solution, because the dissolved solid occupies volume. For peptide masses of a few milligrams in a millilitre or more of diluent the effect is on the order of a few thousandths of a millilitre and is negligible against the graduation interval of the syringe. It ceases to be negligible when the solid mass approaches the diluent volume, which does not arise in the cases this tool is used for. | |
| + | 60 | ||
| 54 | == References == | 61 | == References == |
| 55 | {{reflist}} | 62 | {{reflist}} |