Enteroendocrine L cell: difference between revisions
Diff·revision 2 → 3·17:29, 22 Jul 2024
Difference between revision 2 and revision 3 of Enteroendocrine L cell. 2 lines changed; the page grew by 321 bytes.
| Revision 2 — 15:35, 12 Jul 2024 MazdutideMads (talk) convert the receptor-distribution list to a table 1,903 bytes ±0 | Revision 3 — 17:29, 22 Jul 2024 EmptyingElke (talk) correct the direction of the effect on gastric emptying 2,224 bytes +321 | ||
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| 6 | L cells are polarised epithelial cells with microvilli on the apical surface and secretory granules in the basolateral cytoplasm. The apical surface, open to the lumen, serves as the nutrient-sensing compartment; the basolateral surface contains receptors and ion channels that relay signals to the secretory machinery. L cells represent approximately 0.5–1% of all intestinal epithelial cells overall but are far more frequent in the ileum and colon than the duodenum.{{r|furness2013}} | 6 | L cells are polarised epithelial cells with microvilli on the apical surface and secretory granules in the basolateral cytoplasm. The apical surface, open to the lumen, serves as the nutrient-sensing compartment; the basolateral surface contains receptors and ion channels that relay signals to the secretory machinery. L cells represent approximately 0.5–1% of all intestinal epithelial cells overall but are far more frequent in the ileum and colon than the duodenum.{{r|furness2013}} |
| 7 | 7 | ||
| + | 8 | L cells express nutrient-sensing receptors including receptors for free fatty acids (particularly for long-chain and short-chain fatty acids), a glucose transporter for apical glucose sensing, and taste receptors. This array of receptors allows L cells to respond to a broad spectrum of luminal contents.{{r|holst2007}} | |
| + | 9 | ||
| 8 | == References == | 10 | == References == |
| 9 | {{reflist}} | 11 | {{reflist}} |